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| Product Name | CD54, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE). ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505aa transmembrane glycoprotein containing a 29aa cytoplasmic domain, a 23aa transmembrane domain, and a 453aa extracellular domain. Recombinant human ICAM-1 is a 49.5kD glycoprotein comprising the extracellular domain (453aa residues) of ICAM-1. Monomeric glycosylated ICAM-1 migrates at an apparent molecular weight of ~72-80kD by SDS-PAGE analysis under reducing conditions. Source: Recombinant protein corresponding to 453aa residues from human CD54, expressed in CHO cells. Biological Activity: ICAM-1 supported the adhesion of more than 50% PMA-stimulated HSB2 cells to plates coated at 25ug/ml ICAM-1 c |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD54, Recombinant, Human (Intercellular Adhesion Molecule 1, ICAM-1, Major Group Rhinovirus Receptor, ICAM1) |
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| Gene, Accession, CAS # | ICAM1, Gene ID: 3383, SwissProt: P05362 |
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| Catalog # | 219644 |
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| Order / More Info | CD54, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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