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| Product Name | FLT3 Ligand, Recombinant, Human (FMS-like Tyrosine Kinase 3 Ligand) |
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| Description | Purity ~95% (SDS-PAGE). FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers. Source: Recombinant protein corresponding to the receptor-binding domain of human FLT3L, fused at N-terminal to the Fc portion of human IgG1, expressed in CHO cells. Biological Activity: In vitro and in vivo generation of conventional and plasmacytoid dendritic cells (DC). FLT3L increase |
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| Size | 10ug, 3x10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207185 |
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| Order / More Info | FLT3 Ligand, Recombinant, Human (FMS-like Tyrosine Kinase 3 Ligand) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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