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| Product Name | FLT3 Ligand, Recombinant, Human (Fms-Related Tyrosine Kinase 3 Ligand, FLT3 Ligand, FLT3LG, FLT3L) |
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| Description | Purity ~95% (SDS-PAGE). Known to bind to cells that express the tyrosine kinase receptor, FLT3LG promotes long-term expansion and differentiation of human pro-B cells. Human FLT3LG also stimulates the proliferation of cells expressing murine FLT-3 receptors. In combination with SCF and IL3, FLT3LG can cause expansion of cells with the marker spectrum CD34(+)/CD38(-). Alone, FLT3LG supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU-GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. FLT3LG has only marginal effects on progenitors for erythroid cells and megakaryocytes. Recombinant Human FLT3LG is a non-glycosylated, monomeric protein with intra-chain disulfide bonds. Source: Recombinant protein corresponding to human FLT3 Ligand expressed in E. coli. Molecular Weight: ~17.8kD Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human AML5 cells, the ED50 was 1ng/ml. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P49771 |
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| Catalog # | 500016 |
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| Order / More Info | FLT3 Ligand, Recombinant, Human (Fms-Related Tyrosine Kinase 3 Ligand, FLT3 Ligand, FLT3LG, FLT3L) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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