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| Product Name | FLT3 Ligand, Recombinant, Mouse (FLT-3, Flt3 Ligand, Flt3L, SL Cytokine, FLT3LG) |
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| Description | Purity ~95% (SDS-PAGE). FLT-3 ligand promotes long-term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. The human flt-3 ligand also stimulates the proliferation of cells expressing murine flt-3 receptors.n combination with SCF and IL-3 flt-3 ligand can cause expansion of cells with the marker spectrum CD34(+) CD38(-). Alone, flt-3 ligand supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU-GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. Flt-3 ligand only has marginal effects on progenitors for erythroid cells and megakaryocytes. Source: Recombinant protein corresponding to mouse FLT3 Ligand expressed in E. coli. Molecular Weight: ~19kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of human AML5 cells was found to be in the range of 10ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 14256, SwissProt: P49772 |
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| Catalog # | 500018 |
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| Order / More Info | FLT3 Ligand, Recombinant, Mouse (FLT-3, Flt3 Ligand, Flt3L, SL Cytokine, FLT3LG) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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