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| Product Name | Flt3-Ligand, Recombinant, Mouse (Fms-like Tyrosine Kinase 3 Ligand, flk2 Ligand) |
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| Description | Purity ~98% (SDS-PAGE, HPLC). Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Source: Recombinant protein corresponding to 144aa residues from mouse Flt3-Ligand, expressed in E. coli. Molecular Weight: ~16.4kD Biological Activity: Determined by the dose-dependent proliferation of mouse AML5 cells and is typically 5-8ng/ml. Endotoxin: <0.1ng/ug (0.1EU/u) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Murine flt-3-Ligand, flt-3-Ligand, flt3-Ligand, flt 3-Ligand,m-flt-3-Ligand, rm-flt-3-Ligand, recombinant murine flt-3-Ligand, recombinant flt3-Ligand |
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| Gene, Accession, CAS # | Flt3-L, Gene ID: 14256, SwissProt: P49772 |
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| Catalog # | 219772 |
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| Order / More Info | Flt3-Ligand, Recombinant, Mouse (Fms-like Tyrosine Kinase 3 Ligand, flk2 Ligand) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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