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| Product Name | STAT3 Inhibitor XI, STX-0119 |
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| Description | Purity ~90% (HPLC). A cell-permeable oxadiazolyl-quinolinecarboxamide that is shown to selectively suppress STAT3, but not STAT1, STAT5a, or STAT5b, DNA binding activity and prevent IL-6-stimulated STAT3 dimerization in HEK293 cells (by 99% at 100uM), as well as inhibit the expression of STAT3 target genes both in cultures in vitro (effective conc. 50uM) and in SCC3-derived tumors in mice in vivo (160mg/kg/day; p.o.). Formula: C22H14N4O3 Molecular Weight: 382.4 Solubility: DMSO |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | STAT3 Inhibitor XI, STX-0119 (N-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-2-phenylquinoline-4-carboxamide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217810 |
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| Order / More Info | STAT3 Inhibitor XI, STX-0119 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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