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| Product Name | SFRP2, Recombinant, Mouse (Secreted Frizzled Related Protein 2, SARP-1, SDF-5) (BSA Free) |
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| Description | Purity ≥95%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin: ≤1EU/ug (LAL). Secreted Frizzled Related Proteins (sFRPs) are a family of vertebrate proteins which contain homology to the ligand-binding domain of the Frizzled family of transmembrane receptors. The sFRPs are approximately 30-35kD in size and are comprised of 3 domains: a signal sequence; a cysteine-rich domain (CRD) of about 110 amino acids (aa) with high degree of similarity to the Frizzled proteins, including 10 conserved cysteines; and a 175aa conserved hydrophilic carboxy terminal region. Because sFRPs contain a CRD very similar to the region responsible for binding Wnt ligands in Frizzleds, sFRPS are thought to act as soluble antagonists of Wnt signals. sFRP-2, also known as SARP-1, SDF-5, and FRP-2, is expressed during mouse embryogenesis in the eye, brain, neural tube, craniofacial mesenchyme, joints, testis, pancreas, kidney and regions of smooth muscle cell development. Expression in the adult |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAB70795 |
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| Catalog # | S1012-87RX |
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| Order / More Info | SFRP2, Recombinant, Mouse (Secreted Frizzled Related Protein 2, SARP-1, SDF-5) (BSA Free) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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