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| Product Name | CDK2, Recombinant, Human, aa1-298, His-Tag (Cyclin-Dependent Kinase 2) |
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| Description | Purity ~90% (SDS-PAGE). Cyclin-dependent kinase 2, also known as CDK2, phosphorylates CTNNB1, uSP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. This protein acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. This protein is crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Source: Recombinant protein corresponding to aa1-298 from human CDK2, fused to His-tag at C-terminus, expressed in Insect cells. Molecular Weight: ~34.9kD (306aa) Applications: Suitable for use in SDS-PAGE. |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001789 |
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| Catalog # | 218020 |
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| Order / More Info | CDK2, Recombinant, Human, aa1-298, His-Tag (Cyclin-Dependent Kinase 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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