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CDK5/p25, Recombinant, Human, GST-Tag (CDK5: PSSALRE p25: CDK5R1, CDK5P35, CDK5R, NCK5A, p23, p35, p35nck5a) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | CDK5/p25, Recombinant, Human, GST-Tag (CDK5: PSSALRE p25: CDK5R1, CDK5P35, CDK5R, NCK5A, p23, p35, p35nck5a) |
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| Description | Purified (~70-90%). CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25kD protein which is derived proteolytically from a 35kD brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction. Source: Recombinant protein corresponding to human CDK5/p25, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~49kD, 59kD Specific Activity: 595nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_004935 |
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| Catalog # | 499874 |
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| Order / More Info | CDK5/p25, Recombinant, Human, GST-Tag (CDK5: PSSALRE p25: CDK5R1, CDK5P35, CDK5R, NCK5A, p23, p35, p35nck5a) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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