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| Product Name | KIR3DL1, aa361-444, Cytoplasmic Tail, Recombinant, Human, His-Tag |
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| Description | Purity ≥ 95% by SDS PAGE; Purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. The three Ig-domain from of inhibitory killer cell Ig-like receptor 1 (KIR3DL1, NKB1, nkat3, p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DLl recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR, which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. A His-tag fusion protein of KIR3DL1 cytoplasmic tail (aa361-444) was overexpressed as insoluble protein aggregates (inclusion bodies). Molecular Weight: 15kD (132 amino acids) Sequence: MRGSHHHHHH/ GMASMTGGQQ/ MGRDLYDDDD/ KDRWGSTSGT/ IDKLDIEFHL/ WCSNKKNAAV/ MDQEPAGNRT/ ANSEDSDEQD/ PEEVTYAQLD/ HCVFTQRKIT/ RPSQRPKTPP/ TDTILYTELP/ NAKPRSKVVS/ CP |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | KIR3DL1, aa361-444, Cytoplasmic Tail, Recombinant, Human, His-Tag (NKB1, nkat3, p70 KIR, Killer Cell Immunoglobulin (Ig)-like Receptor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K1862-30 |
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| Order / More Info | KIR3DL1, aa361-444, Cytoplasmic Tail, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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