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| Product Name | IL17 A/F, Recombinant, Rat (Interleukin 17 A/F, IL-17A, IL-17F, Interleukin 17A, Interleukin 17F) |
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| Description | Purity ~98% (SDS-PAGE). Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17R receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant rat IL-17AF is a non-glycosylated, disulfide-linked heterodimer. It is comprised of one monomeric subunit each of IL-17A and IL-17F, having a total of 269aa and a molecular weight of 30.7kD. Source: Recombinant protein corresponding to rat IL17 A/F, expressed in E. coli. Molecular Weight: ~30.7kD Biological Activity: The activity determined by the dose-dependent induction of IL-6 production in cultured mouse NIH 3T3 fibroblasts, i |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | IL17 A/F, Gene ID: 301289/ 301291, SwissProt: Q61453, Q5BJ95 |
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| Catalog # | 301238 |
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| Order / More Info | IL17 A/F, Recombinant, Rat (Interleukin 17 A/F, IL-17A, IL-17F, Interleukin 17A, Interleukin 17F) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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