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| Product Name | DNMT3L, Recombinant, Human, aa1-387, His-Tag (DNA (Cytosine-5)-Methyltransferase 3-Like Isoform 2) |
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| Description | Purity ~90% (SDS-PAGE). CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. DNMT3L is a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. It also mediates transcriptional repression through interaction with histone deacetylase 1. Source: Recombinant protein corresponding to aa1-387 from human DNMT3L, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~46.2kD (411aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_787063 |
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| Catalog # | 218108 |
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| Order / More Info | DNMT3L, Recombinant, Human, aa1-387, His-Tag (DNA (Cytosine-5)-Methyltransferase 3-Like Isoform 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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