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| Product Name | NME1, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic potential. Reductions in NME1 expression have been significantly associated with aggressive behavior in melanoma, breast, colon, and gastric carcinomas. On the contrary, high levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas. Recombinant human NME1 was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa1-152 and 152aa of human NME1, expressed in E. coli. Molecular Weight: ~17.1kD Specific Activity: >180unit/ml Unit Definition: One unit will convert 1.0umole each of TDP and ATP to TTP and ADP per minute at pH 7.6 at 25°C in a coupled system with PK/LDH. Endotoxin: <1.0EU/1ug (LAL method) AA |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NME1, Recombinant, Human (Non-metastatic Cells 1, Nucleoside Diphosphate Kinase A, NDP Kinase A, AWD, GAAD, NB, NBS, NDPK-A, NM23, NM23-H1) |
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| Gene, Accession, CAS # | NME1, Gene ID: 4830, SwissProt: P15531 |
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| Catalog # | 301252 |
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| Order / More Info | NME1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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