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| Product Name | Endothelial Tube Formation Assay (In Vitro Angiogenesis Assay) |
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| Description | Background: Angiogenesis, or neovascularization, is the process of generating new blood vessels derived as extensions from the existing vasculature. The principal cells involved are endothelial cells, which line all blood vessels and constitute virtually the entirety of capillaries. Angiogenesis involves multiple steps; to achieve new blood vessel formation, endothelial cells must first escape from their stable location by breaking through the basement membrane. Once this is achieved, endothelia |
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| Size | 50 assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168234 |
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| Order / More Info | Endothelial Tube Formation Assay (In Vitro Angiogenesis Assay) from MYBIOSOURCE INC. |
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| Product Specific References | 1. Grant DS, Kleinman HK, Leblond CP, Inoue S, Chung AE, Martin GR (1985) Am J Anat 174:387-398.2. Jain RK, Schlenger K, Hockel M, Yuan F (1997) Nat Med 3:1203-1208.3. Auerbach R, Auerbach W, Polakowski I (1991) Pharmacol Ther 51:1-11.4. Auerbach R, Akhtar N, Lewis RL, Shinners BL (2000) Cancer Metastasis Rev 19:167-172.5. Madri JA, Pratt BM, Tucker AM (1988) J Cell Biol 106:1375-1384.1. Zhang, J. et al. (2015). Effects of bioactive cements incorporating zinc-bioglass nanoparticles on odontogenic and angiogenic potential of human dental pulp cells. J Biomater Appl. 29:954-964.2. Pessoa, B. S. et al. (2015). Effect of a stable angiotensin-(1-7) analogue on progenitor cell recruitment and cardiovascular function post myocardial infarction. J Am Heart Assoc. doi: 10.1161/JAHA.114.001510.3. Lee, S. J. et al. (2014). Statins, 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90alpha in human colorectal cancer Br J Cancer. 111-497-505.4. Shin, M.R. et al. (2014). TNF-alpha and LPS activate angiogenesis via VEGF and SIRT1 signaling in human dental pulp cells. Int Endod J. 10.1111/iej.12396.5. Edwards, A.K. et al. (2014). A peptide inhibitor of synuclein-gamma reduces neovascularization of human endometriotic lesions. Mol Hum Reprod. 20:1002-1008.6. Cai, X. et al. (2013). Serum amyloid A stimulates cultured endothelial cells to migrate and proliferate: inhibition by the multikinase inhibitor BIBF1120. Clin Exp Pharmacol Physiol. 40:662-670.7. Yu, J.G. et al. (2013). Baroreflex deficiency hampers angiogenesis after myocardial infarction via acetylcholine-alpha7-nicotinic ACh receptor in rats. Eur. Heart J. 34:2412-2420.8. Bid, H. et al. (2013). Dual targeting of the Type 1 Insulin-like Growth Factor Receptor and its ligands as an effective antiangiogenic strategy. Clin. Cancer Res. 19: 2984-2994.9. Cai, C. et al. (2012). SIVmac239-Nef down-regulates cell surface expression of CXCR4 in tumor cells and inhibits proliferation, migration and angiogenesis. Anticancer Res. 23:2759-2768.10. Bid, H. et al. (2012). Potent inhibition of angiogenesis by the IGF-1 receptor-targeting antibody SCH717454 is reversed by IGF-2. Mol. Cancer Ther. 11: 649-659.11. Spencer, M. et al. (2011). Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance. J Clin Endocrinol Metab. 96:E1990-1998.12. Wang, C. et al. (2010). Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer. Eur Urol. 58:418-426.13. Weskamp, G. et al. (2010). Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes. Circ. Res. 106:932-940.14. Hirata, H. et al. (2010). Role of secreted Frizzled-related protein3 in human renal cell carcinoma. Cancer Res. 70:1896-1905.15. Alfano, R.W. et al. (2009). Matrix metalloproteinase-activated anthrax lethal toxin inhibits endothelial invasion and neovasculature formation during in vitro morphogenesis. Mol. Cancer Res. 7:452-461.16. Masamune, A. et al. (2008). Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer. Am. J. Physiol. Gastrointest. Liver Physiol. 295:G709-G717.17. Zou, L. et al. (2007). Rapid xenograft tumor progression in beta-arrestin1 transgenic mice due to enhanced tumor angiogenesis. FASEB J. 22:355-364.18. Nogueras, S. et al. (2007). Coupling of endothelial injury and repair. an analysis using an in vivo experimental model. Am J. Physiol. Heart Circ. Physiol. 294:H708-H713. |
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