| 产品详情 |
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| Product Name | GDC-0449 |
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| Description | MW: 421.3. Purity ≥98% by HPLC. Background: A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691] |
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| Gene, Accession, CAS # | CAS: 879085-55-9 |
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| Catalog # | MBS843144 |
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| Price | |
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| Order / More Info | GDC-0449 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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