| 产品详情 |
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| Product Name | PTK2, Recombinant, Chicken, aa376-683, GST-Tag (Focal Adhesion Kinase 1) |
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| Description | Purity ~90% (SDS-PAGE). Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development, embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), ephrin receptors, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, cre |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Focal adhesion kinase-related non kinase, FRNK, p41/p43FRNK Protein-tyrosine kinase 2p125FAKpp125FAK |
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| Gene, Accession, CAS # | SwissProt: Q00944 |
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| Catalog # | 374925 |
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| Order / More Info | PTK2, Recombinant, Chicken, aa376-683, GST-Tag (Focal Adhesion Kinase 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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