| 产品详情 |
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| Product Name | MAG (Siglec 4a) Fc Chimera, Recombinant, Rat |
| Description | Purity >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. MAG (Myelin Associated Glycoprotein), a type I transmembrane glycoprotein containing five Iglike domains in its extracellular domain is an adhesion molecule belonging to the immunoglobin superfamily. Within this superfamily, MAG, CD22, CD33, Schwann cell myelin protein, and sialoadhesin which bind specifically to cell surface glycan containing sialic acid residues define the Itype sialyl lectin subgroup, also called the sialoadhesin family. Sialoadhesins mediate diverse biological processes through recognition of specific sialyted glycans on cell surface. MAG is expressed on myelinating oligodenrocytes and Schwann cells, and preferentially recognizes α2, 3linked sialic acid on Olinked glycans and gangliosides. MAG exists as two isoforms which differ in the sequence and length of the cytoplasmic tail. The large form (71 kDa) and small form (67 kDa) arise from alternative spliced mRNAs. Althou |
| Size | 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | SwissProt: P07722 |
| Catalog # | M1748-50D |
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| Order / More Info | MAG (Siglec 4a) Fc Chimera, Recombinant, Rat from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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