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| Product Name | Chitinase 3-like 3, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). Endotoxin Level: ≤0.01EU/ug (LAL). Mouse Chitinase 3-like 3 (CHI3L3), also known as ECF-L (eosinophil chemotactic factor-lymphocyte) or Ym1, is a secreted ~45kD glycoprotein that is a member of the glycosyl hydrolase family 18 (chitinase-like) protein family (1-4). Mouse CHI3L3 has no ortholog in humans, but shares 80% and 90% aa sequence identity with rat CHI3L3 and mouse CHI3L4 (also known as Ym2), respectively (3). Mouse CHI3L3 and CHI3L4 share partial overlap in cell type and tissue mRNA expression (2, 5). CHI3L3 is primarily secreted by alveolar and peritoneal macrophages during inflammation, for example, due to nematode infection and airway hyper-responsiveness (2-10). It is considered a marker for alternatively activated macrophages, and is also expressed in bone marrow myeloid precursors, activated microglia, bone marrow-derived immature mast cells, connective tissue-type mast cells, macrophages in erythroblastic islands, neutrophil granules in bone marr |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Chitinase 3-like 3, Recombinant, Mouse (Chitinase-3-like Protein 3, ECF-L, Eosinophil chemotactic cytokine, Secreted protein Ym1, Ym1 ) |
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| Gene, Accession, CAS # | Accession: NP_034022 |
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| Catalog # | C3980-01A |
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| Order / More Info | Chitinase 3-like 3, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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