产品名称 Parathyroid Hormone, intact (PTHi) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL
产品货号 167563
产品价格 现货询价,电话:010-67529703
产品规格 96 tests
产品品牌 UNITED STATES BIOLOGICAL
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Product NameParathyroid Hormone, intact (PTHi) BioAssay™ ELISA Kit
DescriptionPTH (Parathyroid hormone, Parathormone, Parathyrin) is biosynthesized in the parathyroid gland as a pre- proparathyroid hormone, a larger molecular precursor consisting of 115 amino acids. Following sequential intracellular cleavage of a 25-amino acid sequence, preproparathyroid hormone is converted to an intermediate, a 90-amino acid polypeptide, proparathyroid hormone. With additional proteolytic modification, proparathyroid hormone is then converted to parathyroid hormone, an 84 amino acid polypeptide. In healthy individuals, regulation of parathyroid hormone secretion normally occurs via a negative feedback action of serum calcium on the parathyroid glands. Intact PTH is biologically active and clears very rapidly from the circulation with a half-life of less than four minutes1. PTH undergoes proteolysis in the parathyroid glands, but mostly peripherally, particularly in the liver but also in the kidneys and bone, to give N-terminal fragments and longer lived C-terminal and mid-reg
Size96 tests
Concentrationn/a
ApplicationsELISA
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Catalog #167563
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Order / More InfoParathyroid Hormone, intact (PTHi) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL
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