| 产品详情 |
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| Product Name | Parathyroid Hormone, intact (PTHi) BioAssay™ ELISA Kit |
| Description | PTH (Parathyroid hormone, Parathormone, Parathyrin) is biosynthesized in the parathyroid gland as a pre- proparathyroid hormone, a larger molecular precursor consisting of 115 amino acids. Following sequential intracellular cleavage of a 25-amino acid sequence, preproparathyroid hormone is converted to an intermediate, a 90-amino acid polypeptide, proparathyroid hormone. With additional proteolytic modification, proparathyroid hormone is then converted to parathyroid hormone, an 84 amino acid polypeptide. In healthy individuals, regulation of parathyroid hormone secretion normally occurs via a negative feedback action of serum calcium on the parathyroid glands. Intact PTH is biologically active and clears very rapidly from the circulation with a half-life of less than four minutes1. PTH undergoes proteolysis in the parathyroid glands, but mostly peripherally, particularly in the liver but also in the kidneys and bone, to give N-terminal fragments and longer lived C-terminal and mid-reg |
| Size | 96 tests |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | 167563 |
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| Order / More Info | Parathyroid Hormone, intact (PTHi) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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