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| Product Name | Plasminogen, Human, 98% (Profibrinolysin) |
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| Description | Purity ≥ 98% by SDS PAGE. No contaminants detected. Single band by SDS PAGE, IEP, and/or RID. Plasminogen prescursor or profibrinolysin or plasma trypsinogen (human 810 aa, chromosome 6q26) is synthesized in the kidney. It is present in plasma and many other extracellular fluids. Plasminogen is the zymogen in the circulating blood from which plasmin is formed. Plasminogen is a single-chain glycoprotein with 790 amino acid residues (MW ~90-94kD). Various isoelectric forms exist and can be separated by means of isoelectric focusing (IEF). Native plasminogen (glu-plasminogen) has a N-terminal glutamic acid group. Activation to the active form, plasmin, by urokinase involves cleavage at the arg-val bond between residues 560 and 561, resulting in the formation of the 2-chain plasmin molecule held together by 2 disulfide linkages. The heavier chain contains about 411 residues and the lighter chain about 233. The main function of plasmin is the digestion of fibrin in blood clots. Plasmin is a |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P4256-25 |
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| Order / More Info | Plasminogen, Human, 98% (Profibrinolysin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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