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| Product Name | CD40LG, Recombinant, Macaca Mulatta, aa44-261, His-Tag (CD40 Ligand) |
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| Description | Purity ~90% (SDS-PAGE). Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Recombinant protein corresponding to aa44-261 from Macaca mulatta CD40LG, fused to 6X His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~28.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tumor necrosis factor ligand superfamily member 5, CD_antigen: CD154 |
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| Gene, Accession, CAS # | SwissProt: P63304 |
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| Catalog # | 372672 |
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| Order / More Info | CD40LG, Recombinant, Macaca Mulatta, aa44-261, His-Tag (CD40 Ligand) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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