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| Product Name | CD40LG, Soluble, Recombinant, Mouse |
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| Description | Purity ~98% (SDS-PAGE and HPLC). CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to immunodeficiency with hyper-IgM, a disease characterized by failure to produce IgG, IgA and IgE. The soluble form of CD40L is an 18kD protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Recombinant mouse CD40L is a soluble 16.4kD protein containing 149aa comprising the receptor binding TNF-like domain of CD40L. Source: Recombinant protein corresponding to mouse CD40L, expressed in E.coli. Biol |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD40LG, Soluble, Recombinant, Mouse (CD40 Ligand, CD40-L, T-cell Antigen Gp39, TNF-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, CD154, CD40L, TNFSF5, TRAP) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149708 |
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| Order / More Info | CD40LG, Soluble, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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