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| Product Name | CD40 Ligand, active (CD40LG), Recombinant, Human |
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| Description | Purity ≥95% as determined by SDS-PAGE and HPLC. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (ECO:0000269|PubMed:15193700). Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. (ECO:0000269|PubMed:15193700). Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10ng/ml. |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD40-L, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD antigen CD154 |
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| Gene, Accession, CAS # | CD40L_HUMAN, SwissProt: P29965 |
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| Catalog # | 348018 |
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| Price | |
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| Order / More Info | CD40 Ligand, active (CD40LG), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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