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| Product Name | Pepsinogen I (PGI, PGA, Pepsinogen A3/A4/A5, EC 3.4.23.1), Human |
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| Description | Purity ≥90% by SDS-PAGE (identity confirmed by Western blot). Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II). Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis. It has been reported that human Pepsinogen I (PGA) levels were lower in atrophic corpus gastritis than in atrophic antral gastritis, and human pepsinogen I (PGA) levels were lower in advanced gastric cancer than early stage gastric cancer. Synonyms: Pepsinogen A, PG I, PGA, Pepsinogen 1; E.C. Number 3.4.23.1; Gene: PGA3, PGA4, PGA5 Molecular Weight: 45kD Appearance: Supplied as a white, lyophilized powder in Tris-chloride, pH 8.5. Source: Human gastric mucosa Purity: ≥90% by SDS-PAGE (identity confirmed by Western |
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| Size | 100ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Pepsinogen A, PG I, PGA, Pepsinogen 1; E.C. Number 3.4.23.1; Gene: PGA3, PGA4, PGA5 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 396821 |
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| Order / More Info | Pepsinogen I (PGI, PGA, Pepsinogen A3/A4/A5, EC 3.4.23.1), Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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