| 产品名称 |
BTK, Recombinant, Human, His-Tag (Bruton Tyrosine Kinase, AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | BTK, Recombinant, Human, His-Tag (Bruton Tyrosine Kinase, AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK) |
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| Description | Purified (~70-90%). BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments. Source: Recombinant protein corresponding to human BTK, fused at His-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~78kD Specific Activity: 43nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_000061 |
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| Catalog # | 499829 |
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| Price | |
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| Order / More Info | BTK, Recombinant, Human, His-Tag (Bruton Tyrosine Kinase, AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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