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| Product Name | Hnrnpa2b1, Recombinant, Mouse, aa1-353, His-SUMO-Tag (Heterogeneous Nuclear Ribonucleoproteins A2/B1) |
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| Description | Purity ~90% (SDS-PAGE). Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs. Forms hnRNP particles with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. Involved in transport of specific mRNAs to the cytoplasm in oligodendrocytes and neurons: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) or the A2RE11 (derivative 11 nucleotide oligonucleotide) sequence motifs present on some mRNAs, and promotes their transport to the cytoplasm. Specifically binds single-stranded telomeric DNA sequences, protecting telomeric DNA re |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | hnRNP A2/B1 |
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| Gene, Accession, CAS # | SwissProt: O88569 |
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| Catalog # | 373666 |
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| Order / More Info | Hnrnpa2b1, Recombinant, Mouse, aa1-353, His-SUMO-Tag (Heterogeneous Nuclear Ribonucleoproteins A2/B1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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