| 产品详情 |
| Edit |   |
|---|
| Product Name | IL-18 BioAssay™ ELISA Kit (Human) |
|---|
| Description | Interleukin 18 (IL-18), also known as interferon-gamma-inducing factor (IGIF) and IL-1gamma, is a cytokine which shares biologic activities with IL-12 and structural similarities with the IL-1 family of proteins. IL-18 was originally cloned from liver cells and has since been shown to be expressed by monocyte/macrophages, osteoblasts and keratinocytes. Caspase-1 (IL-1 beta-converting enzyme) has been implicated in the physiological processing of pro-IL-18 to IL-18. Similarly to IL-12, human IL-18 has been shown to enhance NK cell activity in PBMC cultures. Human IL-18 has also been found to induce the production IFN-gamma and GM-CSF while inhibiting the production of IL-10 by PBMC. On enriched human T cells, human IL-18 can enhance Th1 cytokine production and stimulate cell proliferation via an IL-2-dependent pathway. In the mouse system, IL-18 has been shown to be a costimulatory factor for the activation of Th1, but not Th2, cells. IL-18 was found to selectively enhance the FasL-medi |
|---|
| Size | 48 tests |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | IL-18 BioAssay™ ELISA Kit (Human) (Interleukin-18, IL-18, Iboctadekin, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma, IL18, IGIF, IL1F4, Interleukin-1gamma, IL-1gamma, IL1gamma, IL-1F4) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 360490 |
|---|
| Price | |
|---|
| Order / More Info | IL-18 BioAssay™ ELISA Kit (Human) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|