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| Product Name | Neopterin, Human, BioAssay™ ELISA Kit |
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| Description | Neopterin [D-erythro-neopterin] belongs to the group of pteridines. Neopterin as well as other pteridines are derived in vivo from guanosine-triphophate (GTP). Neopterin represents a precursor molecule of biopterin that is an essential cofactor in neurotransmitter synthesis, and it is also involved in variety of oxidation-reduction reactions in the body. The enzyme GTP-cyclohydrolase-I catalyzes this reaction in monocytes and macrophages. Neopterin is exclusively released by activated macrophages, and can be determined in serum, plasma and other body fluids. Neopterin biosynthesis is closely associated with activation of the cellular immune system. Higher levels of neopterin were found in patients with viral infections. Antigenic stimulation of human peripheral blood mononuclear cells leads to neopterin release into cell culture medium. Gamma Interferon treatment of macrophages in vitro also increases neopterin levels and generates highly reactive oxygen species (ROS). Neopterin is cap |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N1060-49 |
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| Order / More Info | Neopterin, Human, BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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