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| Product Name | E2F6, Recombinant, Human, aa1-281, GST-Tag (Transcription Factor E2F6) |
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| Description | Purity ~90% (SDS-PAGE). Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase. Source: Recombinant protein corresponding to aa1-281 from human E2F6, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~58.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O75461 |
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| Catalog # | 373119 |
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| Order / More Info | E2F6, Recombinant, Human, aa1-281, GST-Tag (Transcription Factor E2F6) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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