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| Product Name | RNASEH2A, Recombinant, Human, aa1-299, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). Ribonuclease H2 subunit A, also known as RNASEH2A, belongs to the RNase HII family and eukaryotic subfamily. Localized to the nucleus, RNASEH2A mediates the removal of Okazaki fragment RNA primers that are present on the lagging strand during DNA replication. RNASEH2A catalyzes the endonucleolytic cleavage of RNA to a 5'-phosphomonoester and is able to bind magnesium or manganese as cofactors. Defects in RNASEH2A are the cause of Aicardi-Goutieres syndrome type 4 (AGS4). Source: Recombinant protein corresponding to human RNASEH2A, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~35.8kD (322aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDLSELE RDNTGRCRLS SPVPAVCRKE PCVLGVDEAG RGPVLGPMVY AICYCPLPRL ADLEALKVAD SKTLLESERE RLFAKMEDTD FVGWALDVLS PNLISTSMLG RVKYNLNSLS HDTATGLIQY ALDQGVNVTQ VFVDTVGMPE TYQARLQQSF PGIEVTVKAK ADALYPVVSA ASICAKVARD QAVKKWQFVE KLQDLDTDYG SGYPNDPKTK AWLKEHVEPV FGFPQFVRFS WRTAQTILEK EAEDVIWEDS ASENQEGLRK ITSYFLNEGS QARPRSSHRY |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RNASEH2A, Recombinant, Human, aa1-299, His-Tag (Ribonuclease H2 Subunit A, AGS4, JUNB, RNASEHI, RNHIA, RNHL) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137188 |
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| Order / More Info | RNASEH2A, Recombinant, Human, aa1-299, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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