| 产品详情 |
| Edit |   |
|---|
| Product Name | GDF-3, Recombinant, Human (Growth/Differentiation Factor-3) |
|---|
| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. GDF-3 is a member of the TGF-beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9.Unlike most TGF-beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers.GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue.The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.Recombinant human GDF-3 is a 26.0kD non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains. Biological Activity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150ng/ml. AA Sequence: AAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG Crossreactivity: Mouse Quality Control: Verified |
|---|
| Size | 5ug, 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 143343 |
|---|
| Price | |
|---|
| Order / More Info | GDF-3, Recombinant, Human (Growth/Differentiation Factor-3) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|