| 产品详情 |
| Edit |   |
|---|
| Product Name | GDF-15, Recombinant, Human (MIC-1, Placental TGFbeta, Prostate differentiation factor) |
|---|
| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. GDF-15 belongs to the TGF-beta cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains. Biological Activity: Determined by a cel |
|---|
| Size | 5ug, 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 143341 |
|---|
| Price | |
|---|
| Order / More Info | GDF-15, Recombinant, Human (MIC-1, Placental TGFbeta, Prostate differentiation factor) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|