| 产品详情 |
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| Product Name | Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49) |
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| Description | Purity ~95%. Non-reduced SDS-PAGE of 15ug on 5-15% polyacrylamide slab gel and staining with Coomassie blue shows only two main bands at 120kD (beta1 subunit) and 145kD (alpha5 subunit). A weak band at 205kD is due to dimerization of the beta 1 subunit. The alpha5 beta1 integrin mediates cell adhesion and migration on fibronectin, a glycoprotein critical for normal vertebrate embryonic development. Indirect evidence reported to date suggests that this receptor also functions in the deposition of fibronectin matrices. Integrin alpha5/beta1 purified from smooth muscle under nondenaturing conditions by affinity chromatography on fibronectin-sepharose. Applications: Suitable for use in Western Blot, Electrophoresis and Functional Studies. In Functional Studies, liposomes containing Integrin alpha5/beta1 adhere to surfaces coated with fibronectin in an RGD-dependent fashion. Other applications have not been tested. |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002205.2, SwissProt: P08648 |
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| Catalog # | I7661-35L |
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| Order / More Info | Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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