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| Product Name | TGF-beta1 BioAssay™ ELISA Kit (Mouse/Rat) |
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| Description | Transforming growth factor (TGF), a `factor' that promoted the transformation of cultured fibroblasts into a tumor-like phenotype, was subsequently found to be more of a tumor suppressor than tumor promoter and to be a mixture of two proteins, TGF-alpha and TGF-beta. Human TGF-beta1 is a 25kD, disulfide-linked, non-glycosylated homodimer. There is nearly 100% sequence conservation across mammalian species. Biological activity requires release of TGF-beta1 from the latent complex. This can be done in vitro by disruption of LAP (e.g. acidification). The mouse, rat, porcine and canine TGF-beta1 cDNAs encode a 390aa residue precursor that contains a 29aa signal peptide and a 361aa pro-protein. Mature mouse TGF-beta1 shows 100%aa sequence identity to mature rat TGF-beta1, and both rat and mouse TGF-beta1 show 99%aa sequence identity with mature porcine, human, and canine TGF-beta1. Mature porcine TGF-beta1 shows absolute identity to both mature human and canine TGF-beta1. Sample Type: Cell |
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| Size | 48 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | TGF-beta1 BioAssay™ ELISA Kit (Mouse/Rat) (Transforming growth factor beta-1, TGF-beta-1, TGFB1, TGFB, TGF beta1, TGFbeta1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 361304 |
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| Order / More Info | TGF-beta1 BioAssay™ ELISA Kit (Mouse/Rat) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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