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| Product Name | EGF BioAssay™ ELISA Kit (Human) (Pro-epidermal growth factor, Epidermal growth factorUrogastrone, EGF) |
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| Description | Epidermal Growth Factor (EGF) was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands. Its actions were shown to induce early eyelid opening, incisor eruption, hair growth inhibition, and stunt growth when injected into newborn mice. Human EGF was isolated from urine based on its inhibitory effect on gastric secretion and named urogastrone, accordingly. EGF is prototypic of a family of growth factors that are derived from membrane-anchored precursors. All members of this family are characterized by the presence of at least one EGF structural unit (defined by the presence of a conserved 6 cysteine motif that forms three disulfide bonds) in their extracellular domain. EGF is initially synthesized as a 130kD precursor transmembrane protein containing 9 EGF units. The mature soluble EGF sequence corresponds to the EGF unit located proximal to the transmembrane domain. The membrane EGF precursor is capable of binding to the EGF receptor |
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| Size | 48 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 360150 |
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| Order / More Info | EGF BioAssay™ ELISA Kit (Human) (Pro-epidermal growth factor, Epidermal growth factorUrogastrone, EGF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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