| 产品详情 |
| Edit |   |
|---|
| Product Name | ALK1, Recombinant, Human, GST-tag |
|---|
| Description | Purified (~70-90%). ALK1 is a serine/threonine-protein kinase receptor R3 precursor that mediates signal by TGFbeta superfamily. ALK1 functions as a TGFbeta type I receptor in endothelial cells and is responsible for human hereditary hemorrhagic telangiectasia (HHT) type II. Distinct Smad proteins (i.e., Smad2/Smad3 and Smad1/Smad5) show interaction with ALK1 and mediate TGFbeta signaling. Northern blot and RT-PCR analysis show that ALK1 specifically induces expression of Smad6, Smad7, Id1, Id2, endoglin, STAT1, and interleukin 1 receptor in endothelial cells. ALK1 expression in inflammatory myofibroblastic tumor of the urinary bladder have also has been reported. Source: Recombinant protein corresponding to human ALK1, fused to GST-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~64kD Specific Activity: 22nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ALK1, Recombinant, Human, GST-Tag (Activin A Receptor, Type II-like 1, ACVRL1, ACVRLK1, ALK1, HHT, HHT2, ORW2, SKR3, ALK1, TSR-I) |
|---|
| Gene, Accession, CAS # | Accession: NM_000020 |
|---|
| Catalog # | 499772 |
|---|
| Price | |
|---|
| Order / More Info | ALK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|