产品名称 ALK4, Recombinant, Human, GST-Tag (ACVR1B, SKR2, ACTRIB, ACVRLK4) from UNITED STATES BIOLOGICAL
产品货号 499774
产品价格 现货询价,电话:010-67529703
产品规格 10ug
产品品牌 UNITED STATES BIOLOGICAL
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Product NameALK4, Recombinant, Human, GST-Tag (ACVR1B, SKR2, ACTRIB, ACVRLK4)
DescriptionPurified (~70-90%). ALK4 is a member of the subfamily of receptor ser/thr kinases that mediates signaling by the Activins. ALK4 is expressed in many human tissues, including kidney, pancreas, brain, lung, and liver. Truncated ALK4, predominantly expressed in human pituitary adenomas, function as dominant negative receptors to interfere with wild-type receptor function and blocks the antiproliferative effect of activin possibly contributing to development of human pituitary tumors. ALK4 is able to mediate Nodal signaling in the presence of Cripto during vertebrate development. Source: Recombinant protein corresponding to human ALK4, fused to GST-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~64kD Specific Activity: 16nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL)
Size10ug
Concentrationn/a
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Gene, Accession, CAS #Accession: NM_004302
Catalog #499774
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Order / More InfoALK4, Recombinant, Human, GST-Tag (ACVR1B, SKR2, ACTRIB, ACVRLK4) from UNITED STATES BIOLOGICAL
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