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| Product Name | Gremlin-1, Recombinant, Rat, aa25-184, His-SUMO-Tag (Grem1) |
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| Description | Purity ~90% (SDS-PAGE). Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed. Source: Recombinant protein corresponding to aa25-184 from rat Grem1, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~34.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein |
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| Gene, Accession, CAS # | SwissProt: O35793 |
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| Catalog # | 373527 |
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| Order / More Info | Gremlin-1, Recombinant, Rat, aa25-184, His-SUMO-Tag (Grem1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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