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| Product Name | Cholesterol Efflux, BioAssay™ Kit, Cell-Based, Fluorometric |
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| Description | Cholesterol efflux from the peripheral tissues and cells in atherosclerotic plaque is an initial and critical step in Reverse Cholesterol Transport (RCT). RCT is the process by which extrahepatic cells, including macrophage-derived foam cells in arterial atherosclerotic plaque, transport excessive cholesterol back to the liver for bile acid synthesis and excretion, thus lowering the peripheral lipid burden. A negative correlation has been established between the in vitro efflux of cholesterol from macrophages and atherosclerosis. Sample Type: Serum, isolated or recombinant lipoproteins Intended Use: To screen serum samples or lipoproteins (isolated or recombinant) for cholesterol efflux.?To screen small molecules for their effect on cholesterol efflux (a valuable tool for drug discovery program). Test Principle: The Cholesterol Efflux BioAssay™ is a high-throughput screening assay for measuring cholesterol efflux in cells using fluorescently-labeled cholesterol. This assay provid |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 219657 |
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| Order / More Info | Cholesterol Efflux, BioAssay™ Kit, Cell-Based, Fluorometric from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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