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| Product Name | CTGF, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Secreted by vascular endothelial cells, CTGF is a regulatory protein that has been shown to stimulate the growth of chondrocytes, promote angiogenesis and mediate cell adhesion of fibroblasts and endothelial cells. The binding of CTGF to heparin induces cell migration and adhesion. Mature Human CTGF is a 38kD secreted protein that is comprised of four distinct structural domains (a) IGFBP N-terminal domain (b) VWFC domain (c) TSP type-I domain and (d) C-terminal CTCK domain. Recombinant Human CTGF is an 11.3kD protein monomeric protein that maps to the CTCK domain. Source: Recombinant protein corresponding to human CTGF expressed in E. coli. Molecular Weight: ~11.3kD Biological Activity: Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1-2ug/ml. Endotoxin: <1EU/ug (LAL) |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CTGF, Recombinant, Human (CCN Family Member 2, Hypertrophic Chondrocyte-Specific Protein 24, HCS24, Insulin-Like Growth Factor-Binding Protein 8, IBP-8, IGF-Binding Protein 8, IGFBP-8, Connective Tissue Growth Factor) |
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| Gene, Accession, CAS # | SwissProt: P29279 |
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| Catalog # | 499904 |
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| Order / More Info | CTGF, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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