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| Product Name | PKC theta, Recombinant, Human, GST-Tag (PKC, PRKCQ, PRKCT, nPKC-theta) |
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| Description | Purified (~70-90%). Protein Kinase C, theta (PKC) is important component in the intracellular signaling cascade. Recent studies have suggested that local accumulation of fat metabolites inside skeletal muscle may activate a serine kinase cascade involving PKC-theta leading to defects in insulin signaling and glucose transport in skeletal muscle. Insulin resistance plays a primary role in the development of type 2 diabetes and may be related to alterations in fat metabolism. PKC-theta is a crucial component mediating fat-induced insulin resistance in skeletal muscle and is a potential therapeutic target for the treatment of type 2 diabetes. Source: Recombinant protein corresponding to human PKC theta, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~110kD Specific Activity: 910nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_006257 |
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| Catalog # | 500395 |
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| Order / More Info | PKC theta, Recombinant, Human, GST-Tag (PKC, PRKCQ, PRKCT, nPKC-theta) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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