| 产品详情 |
| Edit |   |
|---|
| Product Name | Elastase, Neutrophil, Recombinant, Mouse |
|---|
| Description | Purity ~95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: ≤1EU/ug (LAL). Neutrophil Elastase (ELA2), also known as polymorphonuclear leukocyte elastase, is a serine protease belonging to the chymotrypsin family. Located primarily in the azurophil granules of polymorphonuclear leukocytes, ELA2 function is the degradation of many extracellular matrix macromolecules. alpha-1 Antitrypsin (Serpin A1) and secretory leukocyte protease inhibitor (SLPI) have been shown to inhibit ELA2 activity. This protein may be involved in lung emphysema, cystic fibrosis, the adult respiratory distress syndrome (ARDS), rheumatoid arthritis, tumor invasion and infectious diseases. The purified recombinant mouse ELA2 does not contain the last five amino acid residues of the deduced amino acid sequence (NP_056594). Murine myeloma cell line, NSO-derived Ser27-Arg260 with a C-terminal 10-His tag (NP_056594). SDS-PAGE: 34kD, Reducing conditions Specific Activity: ~ |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ELA2, Polymorphonuclear Leukocyte Elastase |
|---|
| Gene, Accession, CAS # | Accession: NP_056594 |
|---|
| Catalog # | E2230-27 |
|---|
| Price | |
|---|
| Order / More Info | Elastase, Neutrophil, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|