| 产品详情 |
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| Antigenic Specificity | TLR7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human mouse |
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| Isotype | n/a |
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| Format | Protein G purified |
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| Size | 200ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1) and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described (3). Stimulation of the NFkB signaling pathway by TLR7 suggests that it plays a role in immune response. Applications: Suitable for use in Western Blot. Other applications not tested.Recommended Dilution:Western Blot: 1:500-1:1000 for human Ramos cell lysate and 1:500 for Raw cell lysateOptimal dilutions to be determined by the researcher.Storage and Stability:May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C or colder. Aliquots are stable for at least 24 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 465-483 of human TLR7. |
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| Other Names | TLR7 (Toll Like Receptor 7, TLR-7, PRO285, UNQ248) |
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| Gene, Accession # | SwissProt: Q9NYK1 |
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| Catalog # | T8050-72 |
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| Price | |
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| Order / More Info | TLR7 Antibody from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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