| 产品详情 |
| Edit |   |
|---|
| Product Name | AcCoA Carboxylase 2, Control Peptide, Rat (ACC-2, Acetyl Coenzyme A Carboxylase 2) |
|---|
| Description | Highly purified. Control peptide for A0225-03A (affinity purified antibody) and A0225-03 (antiserum). Synthetic peptide 20aa sequence mapping near the N-terminus of rat ACC-2. No significant sequence homology is seen with ACC-1 or any other protein. Species Sequence Homology: Mouse: 75%; human: 60%. In cells, excess of metabolic fuel is converted into fatty acids in cytosol and oxidized later in mitochondria to generate ATP and acetyl-CoA. In fatty acid synthesis, catalytic formation of malonyl-CoA (precursor for long-chain fatty acyl-CoA, LCFA-CoA) from acetyl-CoA by Acetyl-CoA carboxylase (ACC-1) is the rate limiting step. The translocation of LCFA-CoA from cytosol to mitochondria is catalyzed by two carnitine palmitoyl transferases (CPT-1 & CPT-2) and regulated by ACC-2, the rate limiting step of mitochondrial fatty acid b-oxidation. Activities of ACC-1 and 2 are regulated by their phosphorylation by 5'-AMP-activated protein kinase (AMPK). Diabetes deranges AMPK master-switch and re |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | A0225-03B |
|---|
| Price | |
|---|
| Order / More Info | AcCoA Carboxylase 2, Control Peptide, Rat (ACC-2, Acetyl Coenzyme A Carboxylase 2) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|