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| Product Name | CCR8, Blocking Peptide (TER1, CKR-L1, ChemR1, Chemokine Receptor 8, CC-CKR-8) |
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| Description | Peptide corresponding to amino acids 183 to 201 of human CCR8, which locate in the second extracellular loop (1-3). CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1 (1-4). The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains (5). CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines. Applications: Suitable for use in blocking the activity of anti-CCR8 (Catalog #C2100). |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2100P |
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| Order / More Info | CCR8, Blocking Peptide (TER1, CKR-L1, ChemR1, Chemokine Receptor 8, CC-CKR-8) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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