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| Product Name | CodA, Recombinant, E. coli, aa2-427, His-Tag (Cytosine Deaminase) |
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| Description | Purity ~90% (SDS-PAGE). Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deamination of isoguanine, a mutagenic oxidation product of adenine in DNA, and of isocytosine. To a lesser extent, also catalyzes the conversion of 5-fluorocytosine (5FC) to 5-fluorouracil (5FU); this activity allows the formation of a cytotoxic chotherapeutic agent from a non-cytotoxic precursor. Source: Recombinant protein corresponding to aa2-427 from E. coli codA, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~49.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cytosine aminohydrolaseIsoguanine deaminase1 |
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| Gene, Accession, CAS # | SwissProt: P25524 |
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| Catalog # | 372818 |
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| Order / More Info | CodA, Recombinant, E. coli, aa2-427, His-Tag (Cytosine Deaminase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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