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| Product Name | Angiotensin I, Human (Angiotensin-1, Ang I) |
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| Description | Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system. Angiotensin I is formed by the action of renin on angiotensinogen. Renin is produced in the kidneys in response to both decreased intra-renal blood pressure at the juxtaglomerular cells, or decreased delivery of Na+ and Cl- to the macula densa. If more Na+ is sensed, renin release is decreased. Renin cleaves the peptide bond between the leucine (Leu) and valine (Val) residues on angiotensinogen, creating the 10aa peptide (des-Asp) angiotensin I. Angiotensin I appears to have no biological activity and exists solely as a precursor to angiotensin II. Source: Human Angiotensin I, pure (bioactive). Amino Acid Sequence: Asp-Arg-Val-Tyr-Ile-His-P |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2294-48A1 |
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| Order / More Info | Angiotensin I, Human (Angiotensin-1, Ang I) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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