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| Product Name | Angiotensin II Type 2 Receptor, Human, Control Peptide (AT2) |
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| Description | Highly purified. Control peptide for A2295-07W (affinity purifed antibody) and A2295-07V (antiserum). Synthetic peptide consisting of 18aa sequence mapping near the C-terminus of human AT2. This peptide is predicted to be cytoplasmic. Angiotensin II mediates its action by interacting with membrane receptor, Angiotensin II type 1 receptors. The signal is transmitted via G-proteins that activates a phosphatidylinositol-calcium second messenger system. ATII receptors are integral membrane proteins of approx. 359-363aa and predicted to contain at least 7 transmembrane domains. The N and C-terminus are predicted to extracellular and cytoplasmic, respectively. Three isoforms of ATII receptors have been cloned. In rat type 1a (359aa) is expressed in the liver kidney, aorta, lung, uterus, ovary, spleen, heart, adrenal and vascular smooth muscles (1). Rat Type 1b (also known as AT3; 359aa) is found in liver, kidney, and aorta (2). Type 1c (177aa) has been detected in brain, kidney, liver, splee |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2295-07X |
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| Order / More Info | Angiotensin II Type 2 Receptor, Human, Control Peptide (AT2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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