| 产品名称 |
IL-6, Recombinant, Human, aa29-212 (Interleukin 6, IL-6 GMP, BSF-2, IFN-beta 2, MGI-2A) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | IL-6, Recombinant, Human, aa29-212 (Interleukin 6, IL-6 GMP, BSF-2, IFN-beta 2, MGI-2A) |
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| Description | Purity ~97% (SDS-PAGE). Interleukin 6 (IL-6), also known as interferon-beta 2, 26kD protein and B cell stimulatory factor-2 (BSF-2), is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kD-28kD phosphorylated and variably glycosylated molecule. Mature human IL-6 is 183 amino acids (aa) in length and shares 41% aa sequence identity with mouse and rat IL-6. Alternate splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R) and a signal transducing subunit (gp130). IL-6 binds to IL-6 R, triggering IL-6 R association with gp130 and gp130 |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q75MH2 |
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| Catalog # | 145708 |
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| Price | |
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| Order / More Info | IL-6, Recombinant, Human, aa29-212 (Interleukin 6, IL-6 GMP, BSF-2, IFN-beta 2, MGI-2A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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