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| Product Name | IL-4, Recombinant, Human, Animal Free (BCGF, BCDF, B Cell Stimulating Factor, BSF-1) |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression.Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response.Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes.Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.Recombinant human IL-4 is a 15.1kD globular protein containing 130 amino acid residues. Source: Recombinant protein corresponding to human IL-4 expressed in E. coli. Biological Activity: Determined by its ability to stimulate the proliferation of the IL-6 dependent mouse 7TD1 cells. The expected ED50 is <0.1ng/ml, corre |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BCGF, BCDF, B Cell Stimulating Factor, BSF-1 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208659 |
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| Order / More Info | IL-4, Recombinant, Human, Animal Free (BCGF, BCDF, B Cell Stimulating Factor, BSF-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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